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Botox approved as treatment for overactive bladder

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By Deena Centofanti
Fox 2 News


SOUTHFIELD, Mich. (WJBK) -- Overactive bladder is an embarrassing problem that millions of people live with and many never get help.  The good news is the FDA has just approved Botox as a treatment.

"I was in the bathroom all the time, changing my clothes all the time because of this problem," says Donelle Peglow of Clinton Township.

In her mid-thirties, Peglow never thought she would be suffering from an overactive bladder.  The trouble started after her son was born nine years ago.

"I was constantly interrupted in the middle of something, running to the bathroom or having to leave because [I] had an accident and wasn't prepared," Peglow explains.

"In women it occurs more after childbirth, after menopause, after hysterectomy.  In men, it occurs more associated with enlarged prostate problem or prostate surgery.  Like many other diseases, it's idiopathic.  We don't know why, but it just tends to happen as we get older also," says Beaumont urologist Michael Chancellor.

Overactive bladder is the muscle of the bladder squeezing too often, creating an urgency to urinate and leakage.  Treatments have ranged from drugs to surgery, but now Botox is changing lives.

Chancellor is one of the doctors on the ground floor of the Botox bladder research.

"I'll put the needle into the bladder lining and then inject the Botox and do that in 20 spots in the bladder," he explains.

Once that bladder muscle is relaxed, Beaumont's trial found 90 percent of the time the overactive bladder goes away for months.  And yes, it is a delicate procedure, but Dr. Chancellor says it is bringing back quality of life.

"To be a young woman, to have the thought you can't go out or you have to wear diapers the rest of your life, it really impacts quality of life, keeps you at home, it effects your sexual intimacies, it induces depression, so [being unable to control] your bladder is devastating," Chancellor says.

"There's no words I can say about how happy I am and how much it's helped me," says Peglow.

Peglow says every six months she will gladly get the treatment.  She is being so open in hopes of helping other women who are suffering.

Next Dr. Chancellor will help train doctors all over the country.

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